Ilex paraguariensis A.St.-Hil. improves lipid metabolism in high-fat diet-fed obese rats and suppresses intracellular lipid accumulation in 3T3-L1 adipocytes via the AMPK-dependent and insulin signaling pathways.

Maya KudoMing GaoMisa HayashiYukiko KobayashiJinwei YangTonghua Liu

Published in: Food & nutrition research (2024)

Mate suppressed intracellular lipid accumulation in 3T3-L1 adipocytes and improved lipid metabolism in the epididymal adipose tissue of HFD-fed obese SD rats via the activation of AMPK-dependent and insulin signaling pathways.

Keyphrases

adipose tissue
high fat diet
signaling pathway
insulin resistance
type diabetes
skeletal muscle
pi k akt
glycemic control
reactive oxygen species
fatty acid
epithelial mesenchymal transition
induced apoptosis
cell proliferation
weight loss