A proteomics-based study of the mechanism of oxymatrine to ameliorate hepatic fibrosis in mice.
Jing WuXueqin JinWeihua LiEnqi Liu
Published in: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2024)
OMT inhibited the proliferative capacity of hepatic stellate cells, induced apoptotic properties, and suppressed the development of fibrosis by elevating Cyp2c37/TRP signaling axis activity and upregulating PPAR pathway activity by inhibiting SCP2.