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Bone marrow concentrate injections for the treatment of osteoarthritis: evidence from preclinical findings to the clinical application.

Carola CavalloAngelo BoffaLuca AndrioloSimone SilvaBrunella GrigoloStefano ZaffagniniGiuseppe Filardo
Published in: International orthopaedics (2020)
There is a growing interest in the field of BMAC injections for the treatment of OA, with promising results in preclinical and clinical studies in terms of safety and effectiveness. Nevertheless, the current knowledge is still preliminary. Preclinical research is still needed to optimize BMAC use, as well as high-level large controlled trials to better understand the real potential of BMAC injections for the treatment of patients affected by OA.
Keyphrases
  • bone marrow
  • knee osteoarthritis
  • ultrasound guided
  • randomized controlled trial
  • platelet rich plasma
  • healthcare
  • systematic review
  • cell therapy
  • stem cells
  • replacement therapy
  • human health