Transcriptional regulation of the endocannabinoid system in a rat model of binge-eating behavior reveals a selective modulation of the hypothalamic fatty acid amide hydrolase gene.

Mariangela PucciMaria Vittoria Micioni Di BonaventuraElizabeta ZaplaticFabio BelliaMauro MaccarroneCarlo Cifani Claudio D'Addario

Published in: The International journal of eating disorders (2018)

Our findings suggest that faah transcriptional regulation is a potential biomarker of binge-eating episodes, with a relevant role in the homeostatic regulation of food intake.

Keyphrases

fatty acid
weight loss
physical activity
genome wide
copy number
genome wide identification
gene expression
dna methylation