APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms.

Charidimou AndreasHazel I ZonneveldSara ShamsKejal KantarciAshkan ShoamaneshSaima HilalPaul A YatesGregoire BoulouisHan Kyu NaMarco PasiAllesandro BiffiYuek Ling ChaiJoyce Ruifen ChongLars-Olof WahlundJack R CliffordChristopher ChenM Edip GurolJoshua N GoldsteinDuk L NaFrederik BarkhofSang Won SeoJonathan RosandSteven M GreenbergAnand Viswanathan

Published in: Neurology (2019)

CAA-related vasculopathic changes and fragility associated with APOE ε2+ allele might have a biologically meaningful role in the pathophysiology and severity of cSS.

Keyphrases

systematic review
cognitive decline
high fat diet
meta analyses
mild cognitive impairment
case control
randomized controlled trial
type diabetes
risk assessment
climate change
skeletal muscle
drug induced