Development of an Integrated Sample Amplification Control for Salivary Point-of-Care Pathogen Testing.

Navaporn SritongWinston Wei NgoKarin F K Ejendal Jacqueline C Linnes

Published in: medRxiv : the preprint server for health sciences (2023)

IACs play a crucial role in ensuring user confidence with respect to the accuracy and reliability of at-home and POC molecular diagnostics. We demonstrated the multiplex capability of SARS-COV-2 and human18S ribosomal RNA RT-LAMP without complicating assay design. This generic platform can be extended in a similar manner to include human18S ribosomal RNA IACs into different clinical sample matrices.

Keyphrases

endothelial cells
sars cov
high throughput
induced pluripotent stem cells
nucleic acid
pluripotent stem cells
candida albicans
loop mediated isothermal amplification
sensitive detection