[Evaluation of the effect of Alfuprost MR on detrusor thickness and bladder mass in patients with detrusor hypertrophy caused by benign prostatic hyperplasia].
V Kuzmenko AV Kuzmenko VA Gyaurgiev TPublished in: Urologiia (Moscow, Russia : 1999) (2024)
During the 24-week treatment of patients with BPH, Alfuprost MR demonstrated clinical efficacy not only in reducing voiding symptoms and in improving the QoL, but also a positive effect on detrusor hypertrophy, as evidenced by changes in detrusor thickness and bladder mass index. The absence of any adverse events, including decrease in blood pressure and heart rate, allows us to recommend Alfuprost MR as an effective treatment for LUTS associated with BPH, which reduces detrusor hypertrophy and has a high safety profile and minimal vasodilating effects.
Keyphrases
- benign prostatic hyperplasia
- lower urinary tract symptoms
- heart rate
- blood pressure
- botulinum toxin
- heart rate variability
- spinal cord injury
- contrast enhanced
- magnetic resonance imaging
- randomized controlled trial
- hypertensive patients
- type diabetes
- depressive symptoms
- blood glucose
- sleep quality
- study protocol
- smoking cessation
- placebo controlled