Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight.

William David Thompson Robin N BeaumontAlan KuangNicole M WarringtonYingjie JiJessica TyrrellAndrew R WoodDenise M ScholtensBridget A KnightDavid M EvansWilliam L LoweGillian SantorelliRaq AzadDan MasonAndrew T HattersleyTimothy M FraylingHanieh YaghootkarMaria Carolina BorgesDeborah A LawlorRachel M Freathy

Published in: Human molecular genetics (2022)

Fetal genetic predisposition to both higher adult metabolically favorable adiposity and BMI is associated with birthweight. Fetal effects of metabolically favorable adiposity-raising alleles on birthweight are modestly proportional to their effects on future adiposity, but those of BMI-raising alleles are not.

Keyphrases

weight gain
birth weight
gestational age
body mass index
insulin resistance
weight loss
adipose tissue
metabolic syndrome
genome wide
childhood cancer