Innate IFN-lambda responses to dsRNA in the human infant airway epithelium and clinical regulatory factors during viral respiratory infections in early life.
Kyle SalkaMaria ArroyoElizabeth ChorvinskyKarima AbutalebGeovanny F PerezSeth WolfXilei XuchenJered WeinstockMaria J GutierrezMarcos Pérez-LosadaDinesh K PillaiGustavo NinoPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2020)
IFN-lambda responses to dsRNA in the human infant airway epithelium are regulated by p38-MAPK and NF-kB signalling. High in vivo IFN-lambda production is influenced by virus type and associated with recurrent respiratory sick visits in young children.