Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats ( Artibeus jamaicensis ) Transduced with Human ACE2.
Bradly BurkeSavannah M RochaShijun ZhanMiles EckleyClara ReasonerAmin AddetiaJuliette LewisAnna FagrePhillida CharleyJuergen A RichtSusan R WeissRonald B TjalkensDavid VeeslerTawfik AboellailTony SchountzPublished in: bioRxiv : the preprint server for biology (2023)
helper T cell response showed that activated cells expressed the regulatory T cell cytokines IL-10 and TGFβ that may have tempered pulmonary inflammation.
Keyphrases
- sars cov
- induced apoptosis
- endothelial cells
- transcription factor
- oxidative stress
- cell cycle arrest
- pulmonary hypertension
- regulatory t cells
- transforming growth factor
- respiratory syndrome coronavirus
- induced pluripotent stem cells
- angiotensin ii
- dendritic cells
- pluripotent stem cells
- angiotensin converting enzyme
- immune response
- cell proliferation
- coronavirus disease