World Health Organization Influenza-Like Illness Underestimates the Burden of Respiratory Syncytial Virus Infection in Community-Dwelling Older Adults.
Koos KorstenNiels AdriaenssensSamuel CoenenChris C ButlerTheo J M VerheijLouis J BontJoanne G Wildenbeestnull nullPublished in: The Journal of infectious diseases (2022)
The use of ILI underestimated the occurrence of RSV-ARTI in community-dwelling older adults up to 9-fold (11% sensitivity). Because worldwide RSV surveillance depends largely on ILI, there is an urgent need for a better approach to measure the occurrence of RSV disease and the impact of future RSV vaccine introduction. Clinical Trials Registration. NCT03621930.