Pathological manifestation of human endogenous retrovirus K in frontotemporal dementia.
Katherine PhanYing HeYuHong FuNicolas DzamkoSurabhi BhatiaJulian GoldDominic RoweYazi D KeLars M IttnerJohn R HodgesOlivier PiguetMatthew C KiernanGlenda M HallidayWoojin Scott KimPublished in: Communications medicine (2021)
These results suggest that manifestation of HERV-K is associated with bvFTD TDP-43 pathology. Analysis of HERV-K in bvFTD may provide insight into an unrecognized but targetable perturbed pathology.