Improving the diagnosis of tuberculosis: old and new laboratory tools.
Priya SolankiLinzy EltonIsobella HoneyborneMirae ParkGiovanni SattaTimothy D McHughPublished in: Expert review of molecular diagnostics (2024)
This section highlights future advances in diagnosis and infection control. Prevention of prolonged hospital admissions and rapid TAT are of the most benefit to the overall patient experience. Host transcriptional blood markers have been used in treatment monitoring studies and, with appropriate evaluation, could be rolled out in a diagnostic setting. Additionally, the MBLA is being incorporated into latest clinical trial designs. Whole genome sequencing has enhanced epidemiological evidence. Artificial intelligence, along with machine learning, have the ability to revolutionize TB diagnosis and susceptibility testing within the next decade.