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Analytical and Biological Variability of a Commercial Modified Aptamer Assay in Plasma Samples of Patients with Chronic Kidney Disease.

Ruth F DubinRajat DeoYue RenHongzhe LeeHaochang ShouHarold FeldmanPaul KimmelSushrut S WaikarEugene P RheeAdrienne TinJingsha ChenJoseph CoreshAlan S GoTanika KellyPaduranga S RaoTeresa K ChenMark R SegalPeter Ganz
Published in: The journal of applied laboratory medicine (2023)
Intra-assay and within-subject variability for SomaScan in the CKD setting was low and similar to assay variability reported from individuals without CKD. Intra-assay precision was excellent whether samples were collected in an optimal research protocol, as were CRIC samples, or in the clinical setting, as were the Brigham samples.
Keyphrases
  • high throughput
  • chronic kidney disease
  • randomized controlled trial
  • gold nanoparticles
  • liquid chromatography