Analytical and Biological Variability of a Commercial Modified Aptamer Assay in Plasma Samples of Patients with Chronic Kidney Disease.
Ruth F DubinRajat DeoYue RenHongzhe LeeHaochang ShouHarold FeldmanPaul KimmelSushrut S WaikarEugene P RheeAdrienne TinJingsha ChenJoseph CoreshAlan S GoTanika KellyPaduranga S RaoTeresa K ChenMark R SegalPeter GanzPublished in: The journal of applied laboratory medicine (2023)
Intra-assay and within-subject variability for SomaScan in the CKD setting was low and similar to assay variability reported from individuals without CKD. Intra-assay precision was excellent whether samples were collected in an optimal research protocol, as were CRIC samples, or in the clinical setting, as were the Brigham samples.