Aberrant expression of miR-29b-3p influences heart development and cardiomyocyte proliferation by targeting NOTCH2.

Qian YangFang WuYaping MiFeng WangKe CaiXiaoshan YangRanran ZhangLian LiuYawen ZhangYouhua WangXu WangMingqing XuYonghao GuiQiang Li

Published in: Cell proliferation (2020)

This study reveals that miR-29b-3p functions as a novel regulator of cardiac development and inhibits cardiomyocyte proliferation via NOTCH2, which provides novel insights into the aetiology and potential treatment of CHD.

Keyphrases

signaling pathway
poor prognosis
cell proliferation
angiotensin ii
heart failure
left ventricular
risk assessment
binding protein
long non coding rna
smoking cessation