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Safety and efficacy of linaclotide in children aged 2-5 years with functional constipation: Phase 2, randomized study.

Carlo Di LorenzoJon RobertGerardo Rodriguez-AraujoValentina ShakhnovichWangang XieSamuel NurkoMiguel Saps
Published in: Journal of pediatric gastroenterology and nutrition (2024)
Linaclotide was well tolerated in this pediatric population and an efficacy trend was seen with linaclotide 72 μg versus placebo.
Keyphrases
  • young adults
  • irritable bowel syndrome
  • randomized controlled trial
  • double blind
  • phase iii
  • open label