Retinol binding protein 4 and type 2 diabetes: from insulin resistance to pancreatic β-cell function.
Jiahua FanJinxing HuPublished in: Endocrine (2024)
More mechanistic studies are needed to determine the role of RBP4 in the onset of T2DM, especially in terms of pancreatic β-cell function. In addition, further studies are required to evaluate the effects of drug intervention, lifestyle intervention, and bariatric surgery on RBP4 levels to control T2DM and the role of reducing RBP4 levels in improving insulin sensitivity and pancreatic β-cell function.
Keyphrases
- type diabetes
- insulin resistance
- bariatric surgery
- randomized controlled trial
- glycemic control
- binding protein
- weight loss
- metabolic syndrome
- cardiovascular disease
- case control
- adipose tissue
- physical activity
- high fat diet
- emergency department
- obese patients
- skeletal muscle
- polycystic ovary syndrome
- adverse drug
- electronic health record