An adiponectin receptor agonist promote osteogenesis via regulating bone-fat balance.

Hanghang LiuShibo LiuHuanzhong JiQiucheng ZhaoYao LiuPei HuEn Luo

Published in: Cell proliferation (2021)

Our study demonstrated a pro-osteogenic, anti-adipogenic and anti-osteoclastogenic effect of adiponectin receptor activation in young mice, which suggested adiponectin receptor signalling was involved in bone regeneration and bone-fat balance regulation.

Keyphrases

bone regeneration
metabolic syndrome
insulin resistance
adipose tissue
mesenchymal stem cells
high fat diet induced
bone mineral density
bone marrow
fatty acid
binding protein
skeletal muscle
postmenopausal women
anti inflammatory
body composition
soft tissue
wild type