Does Armodafinil Improve Driving Task Performance and Weight Loss in Sleep Apnea? A Randomized Trial.

Julia L ChapmanElizabeth A CayananCamilla M HoyosYasmina SerinelMaria ComasBrendon J YeeKeith K H WongRonald R GrunsteinNathaniel S Marshall

Published in: American journal of respiratory and critical care medicine (2019)

Armodafinil did not improve driving task performance at the primary endpoint of 6 months. Armodafinil might be a useful adjunctive to weight loss in patients with OSA rejecting conventional treatments but this needs to be directly tested in a specifically designed, properly powered clinical trial. Clinical trial registered with Australian and New Zealand Clinical Trials Registry (ACTRN 12611000847910).

Keyphrases

clinical trial
weight loss
sleep apnea
positive airway pressure
obstructive sleep apnea
bariatric surgery
roux en y gastric bypass
phase ii
gastric bypass
open label
double blind
study protocol
phase iii
glycemic control
randomized controlled trial