Characterization and ex vivo evaluation of excised skin samples as substitutes for human dermal barrier in pharmaceutical and dermatological studies.
Dorottya KocsisVictoria KlangEva-Maria SchweigerZsófia Varga-MedveczkyAnna MihályCsaba PongorZsolt RévészZoltán SomogyiFranciska ErdőPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2022)
A comprehensive evaluation of skin samples of four species was performed. The biophysical and microscopic observations should be considered when selecting drug penetration models and experimental conditions.