NTproBNP in insulin-resistance mediated conditions: overweight/obesity, metabolic syndrome and diabetes. The population-based Casale Monferrato Study.
Stefano BaldassarreSalvatore FragapaniAntonio PaneroDebora FedeleSilvia PinachManuela LucchiariAnna Rita VitaleGiulio MengozziGabriella GrudenGraziella BrunoPublished in: Cardiovascular diabetology (2017)
NT-proBNP levels are lower in overweight/obesity, even in those with diabetes. Both insulin-resistance and chronic low-grade inflammation are involved in this relationship. Further intervention studies are required to clarify the potential role of drugs affecting the natriuretic peptides system on body weight and risk of diabetes.
Keyphrases
- insulin resistance
- type diabetes
- metabolic syndrome
- glycemic control
- low grade
- weight loss
- body weight
- high fat diet induced
- high fat diet
- adipose tissue
- cardiovascular disease
- polycystic ovary syndrome
- weight gain
- skeletal muscle
- randomized controlled trial
- high grade
- physical activity
- uric acid
- oxidative stress
- risk assessment
- body mass index
- cardiovascular risk factors
- drug induced
- human health