Use of Preoperative Magnetic Resonance Imaging to Select Patients with Rectal Cancer for Neoadjuvant Chemoradiation--Interim Analysis of the German OCUM Trial (NCT01325649).
Martin E KreisR RuppertH PtokJ StrassburgP BrosiA LewinM R SchönJ SauerT JungingerS MerkelP Hermaneknull nullPublished in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2015)
Surgical quality determined by pathology workup of specimen was very good in this study. Magnetic resonance imaging guided indication for nCR allows to achieve superb results concerning surrogate parameters for good oncological outcome. Thus, use of neoadjuvant chemoradiation with its potential detrimental side effects may be substantially reduced in selected patients.
Keyphrases
- rectal cancer
- locally advanced
- magnetic resonance imaging
- end stage renal disease
- ejection fraction
- newly diagnosed
- computed tomography
- chronic kidney disease
- contrast enhanced
- clinical trial
- study protocol
- prognostic factors
- squamous cell carcinoma
- radiation therapy
- peritoneal dialysis
- randomized controlled trial
- phase iii
- patient reported outcomes
- patient reported
- double blind