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Discrimination between human populations using a small number of differentially methylated CpG sites: a preliminary study using lymphoblastoid cell lines and peripheral blood samples of European and Chinese origin.

Patrycja Daca-RoszakRoman JaksikJulia PaczkowskaMichał WittEwa Ziętkiewicz
Published in: BMC genomics (2020)
Our results showed that less than 10 pop-CpG sites may distinguish populations of European and Chinese ancestry; importantly, this small composite pop-CpG marker performs well in both lymphoblastoid cell lines and in non-homogenous blood samples regardless of a gender.
Keyphrases
  • dna methylation
  • peripheral blood
  • endothelial cells
  • genetic diversity
  • mental health
  • gene expression
  • pluripotent stem cells