Regular aspirin use and gene expression profiles in prostate cancer patients.
Konrad H StopsackEricka M EbotMary Kathryn DownerTravis A GerkeJennifer R RiderPhilip W KantoffLorelei A MucciPublished in: Cancer causes & control : CCC (2018)
Regular aspirin use may affect ribosome function in prostate tumors. Other putative target genes had similar expression in tumors from aspirin users and non-users. If results are corroborated by experimental studies, a potential benefit of aspirin may be limited to a subset of prostate cancer patients.
Keyphrases
- prostate cancer
- low dose
- cardiovascular events
- gene expression
- antiplatelet therapy
- radical prostatectomy
- end stage renal disease
- newly diagnosed
- anti inflammatory drugs
- poor prognosis
- benign prostatic hyperplasia
- dna methylation
- acute coronary syndrome
- prognostic factors
- coronary artery disease
- percutaneous coronary intervention
- peritoneal dialysis
- cardiovascular disease
- type diabetes
- genome wide
- case control
- bioinformatics analysis