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Effect of Prior Treatment With Fingolimod on Early and Late Response to Rituximab/Ocrelizumab in Patients With Multiple Sclerosis.

Lisa Graille-AvyClemence BoutiereCamille RigolletMarine PerrigueyAudrey RicoSarah DemortierePierre DurozardFrederic HilezianFrederic VelyPierre Bertault-PeresJean PelletierSandra VukusicBertrand Audoin
Published in: Neurology(R) neuroimmunology & neuroinflammation (2024)
For patients switching from FING to RTX/OCR, the risk of disease reactivation within the first 6 months of treatment was increased as compared with patients with other DMT or no previous DMT only when the washout period exceeded 26 days. Neither FING nor other previous DMT reduced the effectiveness of RTX/OCR beyond the first 6 months of treatment.
Keyphrases
  • randomized controlled trial
  • systematic review
  • end stage renal disease
  • newly diagnosed
  • patient reported outcomes