Screening with whole-body magnetic resonance imaging in pediatric subjects with Li-Fraumeni syndrome: A single institution pilot study.
Allison F O'NeillStephan D VossJyothi P JagannathanJunne KamiharaCallie NibeckerElena Itriago-AraujoSerena MasciariErin ParkerMauricio BarretoWendy B LondonJudy E GarberLisa DillerPublished in: Pediatric blood & cancer (2017)
WB-MRI in pediatric subjects is a well-tolerated approach to cancer surveillance despite the need for general anesthesia in some patients. A large multicenter trial would determine true test characteristics and efficacy of this approach for early cancer detection in children at high cancer risk.
Keyphrases
- papillary thyroid
- end stage renal disease
- squamous cell
- ejection fraction
- childhood cancer
- newly diagnosed
- chronic kidney disease
- magnetic resonance imaging
- young adults
- peritoneal dialysis
- lymph node metastasis
- squamous cell carcinoma
- contrast enhanced
- phase iii
- cross sectional
- magnetic resonance
- phase ii
- patient reported
- diffusion weighted imaging
- sensitive detection
- open label