The role of clonal communication and heterogeneity in breast cancer.

Ana Martín-PardillosÁngeles Valls ChivaGemma Bande VargasPablo Hurtado BlancoRoberto Piñeiro CidPedro J GuijarroStefan HümmerEva Bejar SerranoAitor Rodriguez-CasanovaÁngel Diaz-LagaresJosep CastellviSamuel Miravet-VerdeLuis SerranoMaría Lluch-SenarVíctor SebastianAna BribianLaura López-MascaraqueRafael López-LópezSantiago Ramón Y Cajal

Published in: BMC cancer (2019)

These findings support a model where interplay between clones confers aggressiveness, and which may allow identification of the factors involved in cellular communication that could play a role in clonal cooperation and thus represent new targets for preventing tumor progression.

Keyphrases

poor prognosis
single cell
bioinformatics analysis
young adults
childhood cancer