Rate of gestational weight gain and glucose-insulin metabolism among Hispanic pregnant women with overweight and obesity.

Even in the absence of gestational diabetes, rGWG was inversely associated with beta-cell function in a high-risk population of Hispanic pregnant women with overweight and obesity. Beta-cell decline is an established risk factor for transition to type-2 diabetes, and these cross-sectional findings highlight rGWG as a potentially modifiable contributor to this process.