[ 68 Ga]Ga-PSMA-11 PET/CT has potential application in predicting tumor HIF-2α expression and therapeutic response to HIF-2α antagonists in patients with RCC.

Longxiyu MengShun ZhangJie GaoQinfeng XuYao FuYi-Hua ZhouFeng WangHong-Qian Guo

Published in: European radiology (2022)

Ga]Ga-PSMA-11 PET/CT was the most significant predictor of HIF-2α expression level. • This probability could help predict the therapeutic response of patients with RCC to HIF-2α antagonists.

Keyphrases

pet ct
poor prognosis
endothelial cells
positron emission tomography
binding protein
long non coding rna
computed tomography