Long-term outcomes of intravitreal activated protein C injection for ischemic central retinal vein occlusion: an extension trial.
Chikako HaraMotohiro KameiHirokazu SakaguchiNagakazu MatsumuraSusumu SakimotoMihoko SuzukiKentaro NishidaYoko FukushimaKohji NishidaPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2021)
No complications were associated with intravitreal APC, the clinical course improved, and improved RNP was maintained for the long term, suggesting that intravitreal APC may be an alternative treatment for CRVO.
Keyphrases
- diabetic retinopathy
- vascular endothelial growth factor
- age related macular degeneration
- optical coherence tomography
- clinical trial
- study protocol
- risk factors
- endothelial cells
- phase iii
- randomized controlled trial
- ultrasound guided
- ischemia reperfusion injury
- protein protein
- binding protein
- combination therapy
- oxidative stress
- amino acid
- open label