Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial.

Jayant S VaidyaMax BulsaraMichael BaumFrederik WenzSamuele MassarutSteffi PigorschMichael AlvaradoMichael DouekChristobel SaundersHenrik L FlygerWolfgang EiermannChris Brew-GravesNorman R WilliamsIngrid PotykaNicholas RobertsMarcelle BernsteinDouglas BrownElena SperkSiobhan LawsMarc SütterlinTammy CoricaSteinar LundgrenDennis HolmesLorenzo VinanteFernando BozzaMontserrat PazosMagali Le Blanc-OnfroyGünther GruberWojciech PolkowskiKonstantin J DedesMarcus NiewaldJens BlohmerDavid McCreadyRichard HoeferPond KelemenGloria PetraliaMary FalzonDavid J JosephJeffrey S Tobias

Published in: BMJ (Clinical research ed.) (2020)

ISRCTN34086741, NCT00983684.

Keyphrases

early breast cancer
clinical trial
open label
double blind
early stage
phase ii
study protocol
cancer therapy
locally advanced
radiation therapy
radiation induced
phase iii
patients undergoing
placebo controlled
randomized controlled trial
squamous cell carcinoma
drug delivery