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Separate and combined effects of empagliflozin and semaglutide on vascular function: A 32-week randomized trial.

Liv VernstrømSøren GullaksenSteffen S SørensenKristian Løkke FunckEsben LaugesenPer L Poulsen
Published in: Diabetes, obesity & metabolism (2024)
Empagliflozin, semaglutide, or their combination did not reduce arterial stiffness. Combination treatment showed a substantial and clinically important reduction in 24-h systolic BP compared with either treatment alone. Combination treatment increased glycaemic time in range without increasing the risk of hypoglycaemia.
Keyphrases
  • type diabetes
  • blood pressure
  • heart failure
  • randomized controlled trial
  • clinical trial
  • left ventricular
  • atrial fibrillation
  • replacement therapy