Lower extremity MRI following 10-week supervised exercise intervention in patients with diabetic peripheral neuropathy.
Ryan BrownAzadeh SharafiJill M SladeAntonio ConvitNathan DavisSteven BaeteHeather MiltonKenneth J MroczekPatricia M KludingRavinder R RegatteProdromos ParasoglouSmita RaoPublished in: BMJ open diabetes research & care (2021)
The 10-week supervised exercise intervention program successfully reduced adiposity and altered resting tissue properties in the lower leg in DPN. Gastrocnemius mitochondrial oxidative capacity and tibial nerve microarchitecture changes were not observed, either due to lack of response to therapy or to lack of measurement sensitivity.
Keyphrases
- randomized controlled trial
- high intensity
- machine learning
- resistance training
- type diabetes
- magnetic resonance imaging
- total knee arthroplasty
- oxidative stress
- heart rate
- contrast enhanced
- insulin resistance
- placebo controlled
- wound healing
- metabolic syndrome
- diffusion weighted imaging
- peripheral nerve
- cell therapy
- replacement therapy