Effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for patients with moderate-to-severe psoriasis: a cohort study from BADBIR.

Oras A AlabasKaleigh J MasonZenas Zee Ngai YiuPhilip J HamptonNick J ReynoldsCaroline M OwenAnthony BewleyPhilip M LawsRichard Bruce WarrenMark LuntCatherine H SmithChristopher E M Grifﬁths

Published in: The British journal of dermatology (2023)

The real-world effectiveness and persistence of acitretin, ciclosporin, FAEs and methotrexate were generally low. Previous non-biologic systemic therapies, male sex, comorbidities and alcohol consumption were risk factors associated with treatment ineffectiveness.

Keyphrases

alcohol consumption
randomized controlled trial
systematic review
high dose
rheumatoid arthritis
high intensity
early onset
low dose
drug induced