Association between partial remission phase in type 1 diabetes and vitamin D receptor Fok1 rs2228570 polymorphism.
Randa Mahmoud MasoudNour Mohamed Abdel-KaderAbdel-Rahman B Abdel-GhaffarSaid Salama MoselhyYasmine Ibrahim ElhenawyPublished in: Journal of pediatric endocrinology & metabolism : JPEM (2024)
Younger age, less extent of metabolic derangements, and expression of a CC "FF" genotype were found to influence the occurrence of PR. Data from the current study showed that the "C" allele could have a protective role on preserving residual β-cell mass and could predict both onset and duration of PR among newly diagnosed T1D. These findings support the growing concept of future tailored precision medicine.
Keyphrases
- newly diagnosed
- type diabetes
- poor prognosis
- risk assessment
- single cell
- cell therapy
- current status
- cardiovascular disease
- big data
- stem cells
- glycemic control
- insulin resistance
- disease activity
- systemic lupus erythematosus
- smoking cessation
- rheumatoid arthritis
- machine learning
- ulcerative colitis
- binding protein
- skeletal muscle
- long non coding rna
- bone marrow
- deep learning