Antibiotic Resistance Genes Among Carbapenem-resistant Enterobacterales (CRE) Isolates of Prapokklao Hospital, Chanthaburi Province, Thailand.
Witawat TunyongWeewan ArsheewaSirijan SantajitThida Kong-NgoenPornpan PumiratNitat SookrungWanpen ChaicumpaNitaya IndrawattanaPublished in: Infection and drug resistance (2021)
This study demonstrates a significantly high prevalence of CRE isolates with the MDR phenotypes. A minority of the isolates carried a single carbapenem-resistant gene, while the majority harbored multiple genes in combination. Regular monitoring of MDR CRE and characterization of their drug resistance are important for guiding treatment, intervention and control of the CRE spread and outbreak in a health-care setting.
Keyphrases
- antibiotic resistance genes
- healthcare
- genetic diversity
- multidrug resistant
- genome wide
- randomized controlled trial
- microbial community
- wastewater treatment
- genome wide identification
- south africa
- copy number
- dna methylation
- anaerobic digestion
- emergency department
- transcription factor
- combination therapy
- acute care
- adverse drug
- replacement therapy