Genetic and biochemical characterization of BIM-1, a novel acquired subgroup B1 MBL found in a Pseudomonas sp. strain from the Brazilian Amazon region.
Cintya de Oliveira SouzaRodrigo CayôKarla Valéria B LimaDanielle M BrasilienseAna Paula StrelingAndré V SiqueiraFelipe Alberto-LeiJosiane T LealCarolina Silva NodariPaula Juliana Pérez-ChaparroLuana N G C LimaMarcelo O LimaBrenda Natasha S CostaThais Karolina L De QueirozPaola J S N SilvaElza M MamizukaMarcelo F MarcondesJohn Anthony MccullochAna Cristina GalesPublished in: The Journal of antimicrobial chemotherapy (2023)
BIM-1 is a novel acquired MBL encoded by a gene carried by mobile genetic elements, which can be transferred to other Gram-negative bacilli (GNB). Because the IEC33019 strain was recovered from a river impacted by a populous metropolitan region with poor basic sanitation and served by limited potable freshwater, it would be important to establish the role of the BIM-1-producing GNB as nosocomial pathogens and/or as colonizers of the riverside population in this geographical region.