The effect of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase gene overexpression in the kynurenine pathway on the expression levels of indoleamine 2,3-dioxygenase 1 and interferon-γ in inflammatory conditions: an in vitro study.
Marzieh RostaminejadAbdolmohamad RostamiAbbas Behzad-BehbahaniGholam Reza Rafiei DehbidiTahereh KalantariPublished in: Molecular biology reports (2021)
Acmsd gene overexpression in inflammatory conditions can reduce the expression levels of the Ido1 gene, and its regulator, Ifn-γ. Consequently, it may be considered as a novel regulatory factor in the KP balance.