Analysis of multiple gene co-expression networks to discover interactions favoring CFTR biogenesis and ΔF508-CFTR rescue.

Matthew D StrubLong GaoKai TanPaul B McCray

Published in: BMC medical genomics (2021)

The ability of the M-module to identify dynamic modules involved in ΔF508 rescue provides a novel approach for studying CFTR biogenesis and identifying candidate suppressors of ΔF508.

Keyphrases

cystic fibrosis
poor prognosis
copy number
binding protein
gene expression
network analysis