Palladium(II)-Stabilized Pyridine-2-Diazotates: Synthesis, Structural Characterization, and Cytotoxicity Studies.
Alexander G TskhovrebovAnna A VasilevaRichard GoddardTina RiedelPaul J DysonVladimir N MikhaylovTatiyana V SerebryanskayaViktor N SorokoumovMatti HaukkaPublished in: Inorganic chemistry (2018)
Well-defined diazotates are scarce. Here we report the synthesis of unprecedented homoleptic palladium(II) diazotate complexes. The palladium(II)-mediated nitrosylation of 2-aminopyridines with NaNO2 results in the formation of metal-stabilized diazotates, which were found to be cytotoxic to human ovarian cancer cells.