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Cell phone digital microscopy using an oil droplet.

Nicole Anna SzydlowskiHaoran JingMohamed AlqashmiYing Samuel Hu
Published in: Biomedical optics express (2020)
We introduce an accessible cell phone imaging method using small droplets of microscope immersion oil and consumer-grade oils. Oil droplets were more resistant to evaporation than water droplets, and they resolved cellular structures that were visible using a 20x/0.75 objective. We optically characterized the droplets using a cell phone screen and resolution target. We further obtained cellular resolution images of an onion epidermis and a zea stem cross-section sample. Our droplet-based method enables stable optical imaging for diagnostic and educational purposes without custom setups, specialized components, or manufacturing processes.
Keyphrases
  • single cell
  • high resolution
  • high throughput
  • cell therapy
  • single molecule
  • fatty acid
  • optical coherence tomography
  • mass spectrometry
  • photodynamic therapy
  • social media
  • bone marrow