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Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects.

Hyounggyoon YooYun KimIn-Jin JangKyung-Sang YuSeung Hwan Lee
Published in: Drug design, development and therapy (2020)
Evogliptin and glimepiride had no PK interactions when co-administered, while the combination therapy showed an additive glucose-lowering effect compared to those of evogliptin or glimepiride monotherapy.
Keyphrases
  • combination therapy
  • blood glucose
  • type diabetes
  • randomized controlled trial
  • adipose tissue
  • metabolic syndrome