Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention.

Nicolas A Giraldo Esther Drill Baby A Satravada Imane El Dika Angela Rose Brannon Josephine Kam Tai K Dermawan Abhinita Mohanty Kerem Ozcan Debyani Chakravarty Ryma Benayed Efsevia Vakiani Ghassan K Abou-Alfa Ritika Kundra Nikolaus Schultz Bob T Li Michael F Berger James J Harding Marc Ladanyi Eileen M O'Reilly William R Jarnagin Chad M Vanderbilt Olca Basturk Maria E Arcila

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

GBC is a genetically diverse malignancy. This large-scale genomic analysis revealed alterations with potential prognostic and therapeutic implications and provides guidance for the development of targeted therapies.

Keyphrases

randomized controlled trial