The effects of the DNA Demethylating reagent, 5-azacytidine on SMCHD1 genomic localization.

S MassahJ JubeneF J S LeeT V BeischlagG G Prefontaine

Published in: BMC genetics (2020)

These findings provide novel insights on DNA methylation directed function of SMCHD1 in regulating expression of genes associated with central nervous system development that impact future drug development strategies.

Keyphrases

dna methylation
poor prognosis
copy number
circulating tumor
genome wide
gene expression
current status
single molecule
cell free
cerebrospinal fluid
binding protein
long non coding rna
nucleic acid