CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate.

Friederike GutmannCosimo JannFilipa PereiraAndreas JohanssonLars M SteinmetzKiran Raosaheb Patil

Published in: Biotechnology for biofuels (2021)

Our study confirms previously known genetic elements and uncovers new targets towards designing more robust yeast strains for the utilization of lignocellulose hydrolysate as sustainable feedstock, and, more broadly, paves the way for applying CRISPRi screens to improve industrial fermentation processes.

Keyphrases

genome wide
saccharomyces cerevisiae
dna methylation
high throughput
copy number
escherichia coli
heavy metals
cell wall
gene expression
single cell