Serum Levels of T Cell Immunoglobulin and Mucin-Domain Containing Molecule 3 in Patients with Systemic Lupus Erythematosus.

Tomoyuki AsanoNaoki MatsuokaYuya FujitaHaruki MatsumotoJumpei TemmokuMakiko Yashiro-FuruyaShuzo SatoEiji SuzukiHiroko KobayashiHiroshi WatanabeKiyoshi Migita

Published in: Journal of clinical medicine (2020)

Circulating sTIM-3 levels are elevated in SLE patients, and serum sTIM-3 levels are associated with SLE disease activity and SLE-related organ damage. The data indicate a possible link between the TIM-3/Gal-9 pathway and SLE clinical phenotypes, and further investigation of the TIM-3 pathway in SLE pathophysiology is warranted.

Keyphrases

disease activity
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
ejection fraction
newly diagnosed
oxidative stress
prognostic factors
big data
machine learning
deep learning
patient reported