Muscle-Specific Micro-Ribonucleic Acids miR-1-3p, miR-133a-3p, and miR-133b Reflect Muscle Regeneration After Single-Dose Zoledronic Acid Following Rotator Cuff Repair in a Rodent Chronic Defect Model.

Jakob E SchandaPhilipp HeherMoritz WeiglSusanne DrechslerBarbara SchädlJohanna PruellerRoland KocijanPhilipp R HeubererMatthias HacklChristian MuschitzJohannes GrillariHeinz RedlXaver FeichtingerChristian FialkaRainer Mittermayr

Published in: The American journal of sports medicine (2022)

Adjuvant treatment with zoledronic acid may improve muscle regeneration after chronic RCR in humans, thus counteracting fatty muscle infiltration and atrophy.

Keyphrases

skeletal muscle
stem cells
rotator cuff
early stage
fatty acid
combination therapy