PTEN regulates proliferation and osteogenesis of dental pulp cells and adipogenesis of human adipose-derived stem cells.

Nunthawan NowwaroteThanaphum OsathanonBenjamin P J FournierThanakorn TheerapanonSomchai YodsangaPaksinee KamolratanakulThantrira PorntaveetusVorasuk Shotelersuk

Published in: Oral diseases (2021)

PTEN regulates proliferation, enhances osteogenesis of hDPs, and induces adipogenesis of hADSCs. The gain-of-function PTEN variant, p.Gln97*, enhances osteogenic ability of PTEN in hDPs.

Keyphrases

pi k akt
signaling pathway
cell proliferation
cell cycle arrest
induced apoptosis
endothelial cells
mesenchymal stem cells
bone marrow
metabolic syndrome
high fat diet induced
induced pluripotent stem cells
bone regeneration
pluripotent stem cells