Pregnancy and neonatal outcomes of COVID-19: coreporting of common outcomes from PAN-COVID and AAP-SONPM registries.
Edward MullinsM L HudakJ BanerjeeT GetzlaffJ TownsonK BarnetteR PlayleA PerryT BourneChristoph C Leesnull nullPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)
The findings from the UK and USA registries of pregnancies with SARS-CoV-2 infection were remarkably concordant. Preterm delivery affected a higher proportion of women than expected based on historical and contemporaneous national data. The proportions of pregnancies affected by stillbirth, a SGA infant or early neonatal death were comparable to those in historical and contemporaneous UK and USA data. Although maternal death was uncommon, the rate was higher than expected based on UK and USA population data, which is likely explained by underascertainment of women affected by milder or asymptomatic infection in pregnancy in the PAN-COVID study, although not in the AAP-SONPM study. The data presented support strong guidance for enhanced precautions to prevent SARS-CoV-2 infection in pregnancy, particularly in the context of increased risks of preterm delivery and maternal mortality, and for priority vaccination of pregnant women and women planning pregnancy. Copyright © 2021 ISUOG. Published by John Wiley & Sons Ltd.
Keyphrases
- pregnancy outcomes
- pregnant women
- preterm birth
- coronavirus disease
- sars cov
- electronic health record
- respiratory syndrome coronavirus
- gestational age
- big data
- polycystic ovary syndrome
- low birth weight
- birth weight
- risk factors
- cardiovascular events
- randomized controlled trial
- systematic review
- risk assessment
- climate change
- coronary artery disease