Quercetin prevents kidney against diabetes mellitus (type 1) in rats by inhibiting TGF-β/apelin gene expression.

Ashraf Hossein Gholampour Firouzeh Zeinab Karimi Daryabor Gholamreza

Published in: Molecular biology reports (2024)

Quercetin prevents renal dysfunction induced by DM, which might be related to the diminution of lipid peroxidation, strengthening of antioxidant systems, and prevention of the apelin/ TGF-β signaling pathway.

Keyphrases

signaling pathway
gene expression
transforming growth factor
epithelial mesenchymal transition
oxidative stress
pi k akt
dna methylation
mouse model
glycemic control
type diabetes
fatty acid
adipose tissue
metabolic syndrome
skeletal muscle
insulin resistance
endoplasmic reticulum stress
drug induced